234 Use only the diluent supplied by the manufacturer.
Serious systemic, anaphylactic, or neuroparalytic reactions pose a therapeutic dilemma.Shill M, Baynes RD, Miller.Antirabies antibodies neutralize rabies virus and are believed to have a primary role in preventing rabies infection.212 Because inactivated vaccines do not multiply within the body, the acip states that they should not pose any unusual problems for nursing women or their infants.US Rabies Postexposure Prophylaxis Guide Based on Type and Status of Animal Involved236 Animal Type Evaluation and Disposition of Animal Postexposure Prophylaxis Recommendations Dogs, cats, ferrets Healthy and available; confine for 10 days of observation Do not begin prophylaxis unless animal develops clinical signs.
RabAvert rabies vaccine for human use prescribing information.
Centers for Disease Control and Prevention (CDC).
234 Pediatric Use hdcv (Imovax Safety and efficacy in children established.
234 Weigh possibility of an allergic reaction against the potential risk of contracting rabies if the vaccine is not given.
234 236 Immediately report all serious anaphylactic reactions associated with rabies vaccine to the manufacturer and the Vaccine Adverse Event Reporting System (vaers) at or Web.
Centers for Disease Control.
213 236 AAP states that, if possible, the wound should not be sutured.Apr 2016, adacel, tetanus toxoid, reduced Diphtheria Toxoid, Acellular Pertussis Vaccine Adsorbed.234 In addition, use of the vaccine for preexposure vaccination may be indicated in nursing women when a substantial risk of rabies exposure is present.US Rabies Risk Categories and Recommendations for Preexposure Vaccination236 Category of Rabies Risk Nature of Risk Typical Population Preexposure Vaccination Continuous Virus present continuously (often in high concentrations specific exposure likely to go unrecognized; bite, nonbite, or aerosol exposure Rabies research laboratory workers, rabies biologics.In much of the rest of the world, including Latin America, Africa, and Asia, dogs account for most cases of rabies passed on to humans.Also, RIG should not be administered in the same syringe cadeau caramel as vaccine.For children, the anterolateral aspect of the thigh is also acceptable.234 Use immediately after reconstitution.Deltoid area is the only acceptable site for IM administration of rabies vaccine in adults, adolescents, and older children.234 249 Incubation period for rabies infection in humans can range from days to years (usually 13 months).234 Children are at higher risk of rabies exposure compared with adults because of increased potential for animal contact and because they are more likely to be bitten on the head, face, and neck leading to more severe injuries.